CAS Number: 2044-56-6
Linear Formula: CH3(CH2)11OSO3Li
Molecular Weight: 272.33
IUPAC Name: Lithium dodecyl sulfate
Other Names: Dodecyl lithium sulfate, Dodecyl sulfate lithium salt, Lauryl sulfate lithium salt, Lithium lauryl sulfate, LDS
This product is designated as Electrophoresis grade. It has been tested for use in the running buffer (0.5 g LDS/750 ml buffer) for the Weber-Osborn electrophoresis method. Lithium dodecyl sulfate (LDS) is an anionic detergent and surfactant that is frequently used in electrophoresis and chromatography. LDS may be substituted for sodium dodecyl sulfate (SDS) in electrophoresis under cold conditions.
The use of LDS in micellar electrokinetic chromatography has been extensively studied. A report has been published on the partition equilibria of LDS between water and bilayer membranes. LDS has been utilized in protein electrophoresis and proteomics studies.
The three-dimensional structure of the amyloid β-protein fragment 25-35 has been investigated in LDS micelles by two-dimensional 1H NMR. LDS has been used to induce changes in protein conformation.
