CAS Number: 1185-53-1
Linear Formula: NH2C(CH2OH)3 · HCl
Molecular Weight: 157.60
IUPAC Name: 2-Amino-2-hydroxymethyl-propane-1,3-diol hydrochloride
Other Names: TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride
Tris (tris(hydroxymethyl)aminomethane, THAM) is an organic compound with the formula (HOCH2)3CNH2. Tris is extensively used in biochemistry and molecular biology.
In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes.
