CAS Number: 76992-39-8
Linear Formula: NH2C(CH2OH)3 · H3PO4
Molecular Weight: 219.13
IUPAC Name: 2-Amino-2-hydroxymethyl-propane-1,3-diol phosphate
Other Names: Mono(tris[hydroxymethyl]aminomethane) phosphate, Mono-Tris phosphate, Tris phosphate, Tris(hydroxymethyl)-aminomethane phosphate
Tris (tris(hydroxymethyl)aminomethane, THAM) is an organic compound with the formula (HOCH2)3CNH2. Tris is extensively used in biochemistry and molecular biology.
In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes.
